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Rapid induction of transcription of unrearranged S gamma 1 switch regions in activated murine B cells by interleukin 4.

The distribution of immunoglobulin isotypes in activated B lymphocytes can be modulated by interleukin 4 (IL4), which enhances IgG1 and suppresses IgG3. We show here that IL4 induces transcription of the region 5' adjacent to the s gamma 1 switch region within hours after onset of activation of...

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Bibliographic Details
Published in:EMBO J
Main Authors: Esser, C, Radbruch, A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400830/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2785916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03401.x
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