Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia

The majority of patients with acute myeloid leukemia will relapse, and older patients often fail to achieve remission with induction chemotherapy. We explored the possibility that leukemic suppression of innate immunity might contribute to treatment failure. Natural killer cell phenotype and functio...

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Hlavní autoři: Stringaris, Kate, Sekine, Takuya, Khoder, Ahmad, Alsuliman, Abdullah, Razzaghi, Bonnie, Sargeant, Ruhena, Pavlu, Jiri, Brisley, Gill, de Lavallade, Hugues, Sarvaria, Anushruthi, Marin, David, Mielke, Stephan, Apperley, Jane F., Shpall, Elizabeth J., Barrett, A. John, Rezvani, Katayoun
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008119/
https://ncbi.nlm.nih.gov/pubmed/24488563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.087536
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