The Escherichia coli lov gene product connects peptidoglycan synthesis, ribosomes and growth rate.

Mecillinam, a beta-lactam antibiotic which binds specifically to penicillin-binding protein 2 (PBP2), blocks lateral cell-wall elongation, induces spherical morphology and ultimately kills bacteria. We describe here a new mecillinam-resistant mutant of Escherichia coli, the lov mutant. It possesses...

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Bibliographic Details
Main Authors: Bouloc, P, Jaffé, A, D'Ari, R
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400806/
https://ncbi.nlm.nih.gov/pubmed/2540960
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