Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability

AIM: To develop a novel vehicle based on cubosomes as an ophthalmic drug delivery system for flurbiprofen (FB) to reduce ocular irritancy and improve bioavailability. METHODS: FB-loaded cubosomes were prepared using hot and high-pressure homogenization. Cubosomes were then characterized by particle...

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Main Authors: Han, Shun, Shen, Jin-qiu, Gan, Yong, Geng, Hai-ming, Zhang, Xin-xin, Zhu, Chun-liu, Gan, Li
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007820/
https://ncbi.nlm.nih.gov/pubmed/20686524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.98
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