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Identification of Novel Urease Inhibitors by High-Throughput Virtual and in Vitro Screening

[Image: see text] Ureases are important in both agriculture and human health. Bacterial ureases are directly involved in many farm-field problems and pathological conditions. Here, we report a structure-based virtual screening of an in-house compound bank of about 6000 molecular entities by computat...

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Autori principali: Abid, Obaid-ur-Rahman, Babar, Tariq Mahmood, Ali, Farukh Iftakhar, Ahmed, Shahzad, Wadood, Abdul, Rama, Nasim Hasan, Uddin, Reaz, Zaheer-ul-Haq, Khan, Ajmal, Choudhary, M. Iqbal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2010
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007798/
https://ncbi.nlm.nih.gov/pubmed/24900188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100068u
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