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Synthesis and Biochemical Testing of 3-(Carboxyphenylethyl)imidazo[2,1-f][1,2,4]triazines as Inhibitors of AMP Deaminase

[Image: see text] C-Ribosyl imidazo[2,1-f][1,2,4]triazines and 3-[2-(3-carboxyphenyl)ethyl]-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ols represent two classes of known AMP deaminase inhibitors. A combination of the aglycone from the former class with the ribose phosphate mimic from the latter...

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Detalles Bibliográficos
Main Authors: Lindell, Stephen D., Maechling, Simon, Sabina, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2010
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007795/
https://ncbi.nlm.nih.gov/pubmed/24900209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100092a
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