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RalA promotes a direct exocyst–Par6 interaction to regulate polarity in neuronal development

Cell polarization is essential for neuronal development in both the embryonic and postnatal brain. Here, using primary cultures, in vivo postnatal electroporation and conditional genetic ablation, we show that the Ras-like small GTPase RalA and its effector, the exocyst, regulate the morphology and...

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Библиографические подробности
Главные авторы: Das, Amlan, Gajendra, Sangeetha, Falenta, Katarzyna, Oudin, Madeleine J., Peschard, Pascal, Feng, Shanshan, Wu, Bin, Marshall, Christopher J., Doherty, Patrick, Guo, Wei, Lalli, Giovanna
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007768/
https://ncbi.nlm.nih.gov/pubmed/24284074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.145037
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