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RalA promotes a direct exocyst–Par6 interaction to regulate polarity in neuronal development
Cell polarization is essential for neuronal development in both the embryonic and postnatal brain. Here, using primary cultures, in vivo postnatal electroporation and conditional genetic ablation, we show that the Ras-like small GTPase RalA and its effector, the exocyst, regulate the morphology and...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007768/ https://ncbi.nlm.nih.gov/pubmed/24284074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.145037 |
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