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Angiopoiesis and bone regeneration via co-expression of the hVEGF and hBMP genes from an adeno-associated viral vector in vitro and in vivo

AIM: To investigate the therapeutic potential of adeno-associated virus (AAV)-mediated expression of vascular endothelial growth factor (VEGF) and bone morphogenetic protein (BMP). METHODS: Four experimental groups were administered the following AAV vector constructs: rAAV-hVEGF(165)-internal ribos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Chen, Wang, Kun-zheng, Qiang, Hui, Tang, Yi-lun, Li, Qian, Li, Miao, Dang, Xiao-qian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007728/
https://ncbi.nlm.nih.gov/pubmed/20581855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.67
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