Artificial three-dimensional niches deconstruct pancreas development in vitro

In the context of a cellular therapy for diabetes, methods for pancreatic progenitor expansion and subsequent differentiation into insulin-producing beta cells would be extremely valuable. Here we establish three-dimensional culture conditions in Matrigel that enable the efficient expansion of disso...

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Bibliographic Details
Main Authors: Greggio, Chiara, De Franceschi, Filippo, Figueiredo-Larsen, Manuel, Gobaa, Samy, Ranga, Adrian, Semb, Henrik, Lutolf, Matthias, Grapin-Botton, Anne
Format: Artigo
Language:Inglês
Published: Company of Biologists 2013
Subjects:
Techniques and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007719/
https://ncbi.nlm.nih.gov/pubmed/24130330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.096628
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