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Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry

Recent studies have shown that mesothelial progenitors contribute to mesenchymal lineages of developing organs. To what extent the overlying mesothelium contributes to lung development remains unknown. To rigorously address this question, we employed Wt1(CreERT2/+) mice for high-fidelity lineage tra...

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Detalhes bibliográficos
Main Authors: Dixit, Radhika, Ai, Xingbin, Fine, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007715/
https://ncbi.nlm.nih.gov/pubmed/24130328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.098079
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