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TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function
Dysregulation of Wnt signaling is closely associated with human liver tumorigenesis. However, liver cancer-specific Wnt transcriptional programs and downstream effectors remain poorly understood. Here, we identify tribbles homolog 2 (TRIB2) as a direct target of Wnt/TCF in liver cancer, and demonstr...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007693/ https://ncbi.nlm.nih.gov/pubmed/23769673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.013 |
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