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TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function

Dysregulation of Wnt signaling is closely associated with human liver tumorigenesis. However, liver cancer-specific Wnt transcriptional programs and downstream effectors remain poorly understood. Here, we identify tribbles homolog 2 (TRIB2) as a direct target of Wnt/TCF in liver cancer, and demonstr...

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Detalhes bibliográficos
Main Authors: Wang, Jiayi, Park, Joo-Seop, Wei, Yingying, Rajurkar, Mihir, Cotton, Jennifer L., Fan, Qishi, Lewis, Brian C., Ji, Hongkai, Mao, Junhao
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007693/
https://ncbi.nlm.nih.gov/pubmed/23769673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.013
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