Chemokine receptor CXCR3 is important for lung tissue damage and airway remodeling induced by short-term exposure to cigarette smoking in mice

AIM: To investigate the role of chemokine receptor CXCR3 in cigarette smoking (CS)-induced pulmonary damage. METHODS: CXCR3 knockout (CXCR3-/-) mice were used. Differences in airspace enlargement, mRNA expression of matrix metalloproteinases (MMPs), transforming growth factor (TGF) β1, CXCL10 in lun...

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Detalhes bibliográficos
Main Authors: Nie, Li, Liu, Zhen-jia, Zhou, Wei-xun, Xiang, Ruo-lan, Xiao, Yu, Lu, Bao, Pang, Bao-sen, Gao, Jin-ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007663/
https://ncbi.nlm.nih.gov/pubmed/20208554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.192
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