Bupivacaine causes cytotoxicity in mouse C2C12 myoblast cells: involvement of ERK and Akt signaling pathways

AIM: The adverse effects of local anesthetics (LAs) on wound healing at surgical sites have been suggested, and may be related to their cytotoxicity. This study was aimed to compare the cellular toxicity of bupivacaine and lidocaine (two well-known LAs), and to explore the molecular mechanism(s). ME...

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Autori principali: Maurice, Joseph M, Gan, Yan, MA, Fan-xin, Chang, Yong-chang, Hibner, Michael, Huang, Yao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007657/
https://ncbi.nlm.nih.gov/pubmed/20228829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.20
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