Improving reliability and absolute quantification of human brain microarray data by filtering and scaling probes using RNA-Seq

BACKGROUND: High-throughput sequencing is gradually replacing microarrays as the preferred method for studying mRNA expression levels, providing nucleotide resolution and accurately measuring absolute expression levels of almost any transcript, known or novel. However, existing microarray data from...

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Main Authors: Miller, Jeremy A, Menon, Vilas, Goldy, Jeff, Kaykas, Ajamete, Lee, Chang-Kyu, Smith, Kimberly A, Shen, Elaine H, Phillips, John W, Lein, Ed S, Hawrylycz, Mike J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007560/
https://ncbi.nlm.nih.gov/pubmed/24564186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-154
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