Evolution of Bacterial Protein-Tyrosine Kinases and Their Relaxed Specificity Toward Substrates

It has often been speculated that bacterial protein-tyrosine kinases (BY-kinases) evolve rapidly and maintain relaxed substrate specificity to quickly adopt new substrates when evolutionary pressure in that direction arises. Here, we report a phylogenomic and biochemical analysis of BY-kinases, and...

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Bibliografiska uppgifter
Huvudupphovsmän: Shi, Lei, Ji, Boyang, Kolar-Znika, Lorena, Boskovic, Ana, Jadeau, Fanny, Combet, Christophe, Grangeasse, Christophe, Franjevic, Damjan, Talla, Emmanuel, Mijakovic, Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007543/
https://ncbi.nlm.nih.gov/pubmed/24728941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evu056
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