Adenosine 5′-triphosphate stimulates the increase of TGF-β1 in rat mesangial cells under high-glucose conditions via reactive oxygen species and ERK1/2

AIM: To investigate the role of adenosine 5′-triphosphate (ATP)-induced generation of reactive oxygen species (ROS) and phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2) in the production of transforming growth factor-β1 (TGF-β1) in cultured rat glomerular mesangial cells under h...

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Detalhes bibliográficos
Main Authors: Qu, Lin-ping, Xue, Hong, Yuan, Ping, Zhou, Li, Yao, Tai, Huang, Yu, Lu, Li-min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007501/
https://ncbi.nlm.nih.gov/pubmed/19960006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.155
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