Depletion of SLC4A11 Causes Cell Death by Apoptosis in an Immortalized Human Corneal Endothelial Cell Line

PURPOSE. To investigate the effects of SLC4A11 gene depletion in human corneal endothelial cells. METHODS. To achieve stable downregulation of SLC4A11 gene expression in immortalized human corneal endothelial cells (HCECs), short-hairpin RNA (shRNA) targeted against SLC4A11 was used. Cell growth and...

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Hauptverfasser: Liu, Jun, Seet, Li-Fong, Koh, Li Wei, Venkatraman, Anandalakshmi, Venkataraman, Divya, Mohan, Rajiv R., Praetorius, Jeppe, Bonanno, Joseph A., Aung, Tin, Vithana, Eranga N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007482/
https://ncbi.nlm.nih.gov/pubmed/22447871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8724
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