2-Acylamido Analogues of N-Acetylglucosamine Prime Formation of Chitin Oligosaccharides by Yeast Chitin Synthase 2

Chitin, a homopolymer of β1,4-linked N-acetylglucosamine (GlcNAc) residues, is a key component of the cell walls of fungi and the exoskeletons of arthropods. Chitin synthases transfer GlcNAc from UDP-GlcNAc to preexisting chitin chains in reactions that are typically stimulated by free GlcNAc. The e...

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Autores principales: Gyore, Jacob, Parameswar, Archana R., Hebbard, Carleigh F. F., Oh, Younghoon, Bi, Erfei, Demchenko, Alexei V., Price, Neil P., Orlean, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007471/
https://ncbi.nlm.nih.gov/pubmed/24619411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550749
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