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Fatty Acid-binding Protein 5 (FABP5) Regulates Cognitive Function Both by Decreasing Anandamide Levels and by Activating the Nuclear Receptor Peroxisome Proliferator-activated Receptor β/δ (PPARβ/δ) in the Brain

Endocannabinoids modulate multiple behaviors, including learning and memory. We show that the endocannabinoid anandamide (AEA) can alter neuronal cell function both through its established role in activation of the G-protein-coupled receptor CB1, and by serving as a precursor for a potent agonist of...

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Detalhes bibliográficos
Main Authors: Yu, Shuiliang, Levi, Liraz, Casadesus, Gemma, Kunos, George, Noy, Noa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007463/
https://ncbi.nlm.nih.gov/pubmed/24644281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559062
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