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Formulation development and evaluation of metformin chewing gum with bitter taste masking

BACKGROUND: Medicated gums are intended to be chewed and act either locally, absorbed via the buccal mucosa or swallowed with saliva. We prepared the metformin gum to overcome its side effects including vomiting, diarrhea, and abdomen discomfort. Furthermore, it could be useful for those who have sw...

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Main Authors: Mostafavi, Sayed Abolfazl, Varshosaz, Jaleh, Arabian, Saber
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007337/
https://ncbi.nlm.nih.gov/pubmed/24800181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2277-9175.129362
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