Characterization of cardamonin metabolism by P450 in different species via HPLC-ESI-ion trap and UPLC-ESI-quadrupole mass spectrometry

AIM: To characterize the metabolism of cardamonin by the P450 enzymes in human and animal liver microsomes. METHODS: Cardamonin was incubated with both human and animal liver microsomal incubation systems containing P450 reaction factors. High performance liquid chromatography coupled with ion trap...

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Detalhes bibliográficos
Main Authors: He, Yu-qi, Yang, Li, Liu, Yong, Zhang, Jiang-wei, Tang, Jun, Su, Juan, Li, Yuan-yuan, Lu, Yan-liu, Wang, Chang-hong, Yang, Ling, Wang, Zheng-tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007323/
https://ncbi.nlm.nih.gov/pubmed/19767764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.127
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