Epinephrine, phenylephrine, and methoxamine induce infiltrative anesthesia via α1-adrenoceptors in rats

AIM: To assess whether epinephrine, phenylephrine, and methoxamine act via certain subtypes of adrenoceptors to exert their local anesthetic activity. METHODS: We investigated cutaneous anesthesia from adrenoceptor agonists and/or antagonists in conscious, unanesthetized Sprague-Dawley male rats (we...

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Detalhes bibliográficos
Main Authors: Shieh, Ja-ping, Chu, Chin-chen, Wang, Jhi-joung, Lin, Mao-tsun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007178/
https://ncbi.nlm.nih.gov/pubmed/19730427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.129
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