n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2α and telomerase activity

AIM: To investigate the role of hTERT gene expression and AP-2α in n-butylidenephthalide (n-BP)-induced apoptosis in A549 lung cancer cells. METHODS: Viability of A549 cells was measured by MTT assay. Protein expression was determined by Western blot. Telomerase activity was measured using the modif...

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Main Authors: Wei, Chyou-wei, Lin, Chai-ching, Yu, Yung-luen, Lin, Chai-yi, Lin, Po-cheng, Wu, Min-tze, Chen, Cheng-jueng, Chang, Wenliang, Lin, Shinn-zong, Chen, Yi-lin Sophia, Harn, Horng-jyh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007174/
https://ncbi.nlm.nih.gov/pubmed/19701232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.124
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