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Targeting RANKL in metastasis
Acting through its cognate receptor, receptor activator of nuclear factor-κB (RANK), RANK ligand (RANKL) is an essential mediator of osteoclast function and survival. Preclinical data have now firmly established that blockade of tumor-induced osteoclastogenesis by RANKL inhibition will not only prot...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007167/ https://ncbi.nlm.nih.gov/pubmed/24795813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2014.14 |
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