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The role of an inwardly rectifying K(+) channel (Kir4.1) in the inner ear and hearing loss

The KCNJ10 gene which encodes an inwardly rectifying K(+) channel Kir4.1 subunit plays an essential role in the inner ear and hearing. Mutations or deficiency of KCNJ10 can cause hearing loss with EAST or SeSAME syndromes. This review mainly focuses on the expression and function of Kir4.1 potassium...

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Main Authors: Chen, Jing, Zhao, Hong-Bo
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007161/
https://ncbi.nlm.nih.gov/pubmed/24480364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.01.036
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