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Licochalcone Suppresses LXRα-Induced Hepatic Lipogenic Gene Expression through AMPK/Sirt1 Pathway Activation

Licochalcone (LC), a major phenolic retrochalcone from licorice, has anti-inflammatory activity. This study investigated the effects of licochalcone A (LCA) and licochalcone E (LCE) on Liver X receptor-α (LXRα)-mediated lipogenic gene expression and the molecular mechanisms underlying those effects....

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Detalhes bibliográficos
Main Authors: Han, Jae Yun, Park, Sun Hee, Yang, Ji Hye, Kim, Mi Gwang, Cho, Seung Sik, Yoon, Goo, Cheon, Seung Hoon, Ki, Sung Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society Of Toxicology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007039/
https://ncbi.nlm.nih.gov/pubmed/24795795
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