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Prophenoloxidase Activation Is Required for Survival to Microbial Infections in Drosophila

The melanization reaction is a major immune response in Arthropods and involves the rapid synthesis of melanin at the site of infection and injury. A key enzyme in the melanization process is phenoloxidase (PO), which catalyzes the oxidation of phenols to quinones, which subsequently polymerize into...

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Detalhes bibliográficos
Main Authors: Binggeli, Olivier, Neyen, Claudine, Poidevin, Mickael, Lemaitre, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006879/
https://ncbi.nlm.nih.gov/pubmed/24788090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004067
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