Efficacy of a Metalloproteinase Inhibitor in Spinal Cord Injured Dogs

Matrix metalloproteinase-9 is elevated within the acutely injured murine spinal cord and blockade of this early proteolytic activity with GM6001, a broad-spectrum matrix metalloproteinase inhibitor, results in improved recovery after spinal cord injury. As matrix metalloproteinase-9 is likewise acut...

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Detalhes bibliográficos
Main Authors: Levine, Jonathan M., Cohen, Noah D., Heller, Michael, Fajt, Virginia R., Levine, Gwendolyn J., Kerwin, Sharon C., Trivedi, Alpa A., Fandel, Thomas M., Werb, Zena, Modestino, Augusta, Noble-Haeusslein, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006832/
https://ncbi.nlm.nih.gov/pubmed/24788791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096408
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