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Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma

INTRODUCTION: Little is known of the function and clinical significance of intratumoral dysregulation of xenobiotic-metabolizing enzyme expression in breast cancer. One molecular mechanism proposed to explain tamoxifen resistance is altered tamoxifen metabolism and bioavailability. METHODS: To test...

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Библиографические подробности
Главные авторы: Bièche, Ivan, Girault, Igor, Urbain, Estelle, Tozlu, Sengül, Lidereau, Rosette
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC400681/
https://ncbi.nlm.nih.gov/pubmed/15084249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr784
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