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Identification of Risk Factors for Nephrotoxicity in Patients Receiving Extended-Duration, High-Trough Vancomycin Therapy

BACKGROUND: In the past, impurities in vancomycin formulations were thought to contribute to nephrotoxicity. In contrast, when current, purer formulations are dosed at conventional trough levels (i.e., 5–15 mg/L), the incidence of nephrotoxicity is relatively low. Recent guidelines have recommended...

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Autori principali: Contreiras, Claire, Legal, Michael, Lau, Tim T Y, Thalakada, Rosanne, Shalansky, Stephen, Ensom, Mary H H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Canadian Society of Hospital Pharmacists 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006757/
https://ncbi.nlm.nih.gov/pubmed/24799722
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