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GOLPH3 Is Essential for Contractile Ring Formation and Rab11 Localization to the Cleavage Site during Cytokinesis in Drosophila melanogaster

The highly conserved Golgi phosphoprotein 3 (GOLPH3) protein has been described as a Phosphatidylinositol 4-phosphate [PI(4)P] effector at the Golgi. GOLPH3 is also known as a potent oncogene, commonly amplified in several human tumors. However, the molecular pathways through which the oncoprotein G...

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Bibliographic Details
Main Authors: Sechi, Stefano, Colotti, Gianni, Belloni, Giorgio, Mattei, Vincenzo, Frappaolo, Anna, Raffa, Grazia D., Fuller, Margaret T., Giansanti, Maria Grazia
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006750/
https://ncbi.nlm.nih.gov/pubmed/24786584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004305
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