Allele-Specific Genome-wide Profiling in Human Primary Erythroblasts Reveal Replication Program Organization

We have developed a new approach to characterize allele-specific timing of DNA replication genome-wide in human primary basophilic erythroblasts. We show that the two chromosome homologs replicate at the same time in about 88% of the genome and that large structural variants are preferentially assoc...

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Hauptverfasser: Mukhopadhyay, Rituparna, Lajugie, Julien, Fourel, Nicolas, Selzer, Ari, Schizas, Michael, Bartholdy, Boris, Mar, Jessica, Lin, Chii Mei, Martin, Melvenia M., Ryan, Michael, Aladjem, Mirit I., Bouhassira, Eric E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006724/
https://ncbi.nlm.nih.gov/pubmed/24787348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004319
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