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Mutations in Four Glycosyl Hydrolases Reveal a Highly Coordinated Pathway for Rhodopsin Biosynthesis and N-Glycan Trimming in Drosophila melanogaster

As newly synthesized glycoproteins move through the secretory pathway, the asparagine-linked glycan (N-glycan) undergoes extensive modifications involving the sequential removal and addition of sugar residues. These modifications are critical for the proper assembly, quality control and transport of...

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Библиографические подробности
Главные авторы: Rosenbaum, Erica E., Vasiljevic, Eva, Brehm, Kimberley S., Colley, Nansi Jo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006722/
https://ncbi.nlm.nih.gov/pubmed/24785692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004349
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