Drosophila melanogaster Hox Transcription Factors Access the RNA Polymerase II Machinery through Direct Homeodomain Binding to a Conserved Motif of Mediator Subunit Med19

Hox genes in species across the metazoa encode transcription factors (TFs) containing highly-conserved homeodomains that bind target DNA sequences to regulate batteries of developmental target genes. DNA-bound Hox proteins, together with other TF partners, induce an appropriate transcriptional respo...

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Bibliographische Detailangaben
Hauptverfasser: Boube, Muriel, Hudry, Bruno, Immarigeon, Clément, Carrier, Yannick, Bernat-Fabre, Sandra, Merabet, Samir, Graba, Yacine, Bourbon, Henri-Marc, Cribbs, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006704/
https://ncbi.nlm.nih.gov/pubmed/24786462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004303
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