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Cell penetrating peptides released from thermosensitive nanoparticles suppress proinflammatory cytokine response by specifically targeting inflamed cartilage explants
Cell penetrating anti-inflammatory peptide KAFAKLAARLYRKALARQLGVAA (KAFAK) has the ability to suppress pro-inflammatory cytokines TNF-α and IL-6 when released from degradable and non-degradable Poly(NIPAm-AMPS) nanoparticles. In vitro human macrophage model with THP1 human monocytes and ex vivo bovi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006693/ https://ncbi.nlm.nih.gov/pubmed/23041412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2012.09.003 |
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