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Liquiritigenin inhibits Aβ(25–35)-induced neurotoxicity and secretion of Aβ(1–40) in rat hippocampal neurons
AIM: To examine whether liquiritigenin, a newly found agonist of selective estrogen receptor-β, has neuroprotective activity against β-amyloid peptide (Aβ) in rat hippocampal neurons. METHODS: Primary cultures of rat hippocampal neurons were pretreated with liquiritigenin (0.02, 0.2, and 2 μmol/L) p...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Nature Publishing Group
2009
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006661/ https://ncbi.nlm.nih.gov/pubmed/19574995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.74 |
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