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Liquiritigenin inhibits Aβ(25–35)-induced neurotoxicity and secretion of Aβ(1–40) in rat hippocampal neurons

AIM: To examine whether liquiritigenin, a newly found agonist of selective estrogen receptor-β, has neuroprotective activity against β-amyloid peptide (Aβ) in rat hippocampal neurons. METHODS: Primary cultures of rat hippocampal neurons were pretreated with liquiritigenin (0.02, 0.2, and 2 μmol/L) p...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Rui-ting, Zou, Li-bo, Lü, Qiu-jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006661/
https://ncbi.nlm.nih.gov/pubmed/19574995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.74
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