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Calcitonin gene-related peptide stimulates BMP-2 expression and the differentiation of human osteoblast-like cells in vitro

AIM: To investigate whether bone morphogenic protein-2 (BMP-2) expression was involved in calcitonin gene-related peptide (CGRP)-induced osteogenesis in human osteoblast-like cells in vitro. METHODS: MG-63 osteogenic human osteosarcoma cells were treated with CGRP (10-8 mol/L) for 48 h. Cell cycle p...

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Detalhes bibliográficos
Main Authors: Tian, Gang, Zhang, Gang, Tan, Ying-hui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006471/
https://ncbi.nlm.nih.gov/pubmed/23708553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.41
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