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Interferon regulatory factor 8 mediates tumor-induced inhibition of antigen processing and presentation by dendritic cells

INTRODUCTION: Suppression of dendritic cells (DCs) is a crucial mechanism by which tumor cells escape immune recognition and elimination. We have recently reported that MHC class I antigen processing machinery (APM) component expression in human DCs is down-regulated by tumor-derived gangliosides. H...

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Detalhes bibliográficos
Main Authors: Tourkova, Irina L., Shurin, Galina V., Ferrone, Soldano, Shurin, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006356/
https://ncbi.nlm.nih.gov/pubmed/18751977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0579-1
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