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Myofibroblastic Cells Function as Progenitors to Regenerate Murine Livers after Partial Hepatectomy
OBJECTIVE: Smoothened (SMO), a co-receptor of the Hedgehog (Hh) pathway, promotes fibrogenic repair of chronic liver injury. We investigated the roles of SMO+ myofibroblasts (MF) in liver regeneration by conditional deletion of SMO in αSMA+ cells after partial hepatectomy (PH). DESIGN: αSMA-Cre-ER(T...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006344/ https://ncbi.nlm.nih.gov/pubmed/24173292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305962 |
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