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Blind prediction of solvation free energies from the SAMPL4 challenge

Here, we give an overview of the small molecule hydration portion of the SAMPL4 challenge, which focused on predicting hydration free energies for a series of 47 small molecules. These gas-to-water transfer free energies have in the past proven a valuable test of a variety of computational methods a...

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Detalhes bibliográficos
Main Authors: Mobley, David L., Wymer, Karisa L., Lim, Nathan M., Guthrie, J. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006301/
https://ncbi.nlm.nih.gov/pubmed/24615156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-014-9718-2
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