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Deletion of the EphA2 receptor exacerbates myocardial injury and the progression of ischemic cardiomyopathy

EphrinA1-EphA-receptor signaling is protective during myocardial infarction (MI). The EphA2-receptor (EphA2-R) potentially mediates cardiomyocyte survival. To determine the role of the EphA2-R in acute non-reperfused myocardial injury in vivo, infarct size, inflammatory cell density, NF-κB, p-AKT/Ak...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: O'Neal, Wesley T., Griffin, William F., Kent, Susan D., Faiz, Filza, Hodges, Jonathan, Vuncannon, Jackson, Virag, Jitka A. I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006041/
https://ncbi.nlm.nih.gov/pubmed/24795639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00132
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