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“Patch”ing Up Our Tumor Signaling Knowledge

The tumor suppressor Patched1 (Ptch1) possesses well-described roles in regulating sonic hedgehog (SHH) signaling in the skin and preventing the formation of basal cell carcinomas (BCCs). In this issue, Kang et al. extend their previous work to show that a naturally occurring allele of Ptch1 found i...

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Detalles Bibliográficos
Autores principales: Atwood, Scott X., Whitson, Ramon J., Oro, Anthony E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006018/
https://ncbi.nlm.nih.gov/pubmed/23594533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.506
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