Quantitatively Controlling Expression of miR-17∼92 Determines Colon Tumor Progression in a Mouse Tumor Model

The miRNA cluster miR-17∼92 targets mRNAs involved in distinct pathways that either promote or inhibit tumor progression. However, the cellular and molecular mechanisms underlying miR-17∼92 cluster-mediated protumorigenic or anti-tumorigenic effects have not been studied. Herein, we determined that...

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Detalhes bibliográficos
Main Authors: Jiang, Hong, Wang, Ping, Wang, Qilong, Wang, Baomei, Mu, Jingyao, Zhuang, Xiaoying, Zhang, Lifeng, Yan, Jun, Miller, Donald, Zhang, Huang-Ge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005973/
https://ncbi.nlm.nih.gov/pubmed/24681249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.01.037
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