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The Critical Role of IL-15–PI3K–mTOR Pathway in Natural Killer Cell Effector Functions

Natural killer (NK) cells were so named for their uniqueness in killing certain tumor and virus-infected cells without prior sensitization. Their functions are modulated in vivo by several soluble immune mediators; interleukin-15 (IL-15) being the most potent among them in enabling NK cell homeostas...

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Detalhes bibliográficos
Main Authors: Nandagopal, Neethi, Ali, Alaa Kassim, Komal, Amandeep Kaur, Lee, Seung-Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005952/
https://ncbi.nlm.nih.gov/pubmed/24795729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00187
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