Streptozotocin-induced diabetes prolongs twitch duration without affecting the energetics of isolated ventricular trabeculae

BACKGROUND: Diabetes induces numerous electrical, ionic and biochemical defects in the heart. A general feature of diabetic myocardium is its low rate of activity, commonly characterised by prolonged twitch duration. This diabetes-induced mechanical change, however, seems to have no effect on contra...

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Main Authors: Han, June-Chiew, Tran, Kenneth, Nielsen, Poul MF, Taberner, Andrew J, Loiselle, Denis S
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005834/
https://ncbi.nlm.nih.gov/pubmed/24731754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-79
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