Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

A dense mucous layer in the large intestine prevents inflammation by shielding the underlying epithelium from luminal bacteria and food antigens. This mucous barrier is organized around the hyperglycosylated mucin MUC2. Here we show that the small intestine has a porous mucous layer, which permitted...

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Detalhes bibliográficos
Main Authors: Shan, Meimei, Gentile, Maurizio, Yeiser, John R., Walland, A. Cooper, Bornstein, Victor U., Chen, Kang, He, Bing, Cassis, Linda, Bigas, Anna, Cols, Montserrat, Comerma, Laura, Huang, Bihui, Blander, J. Magarian, Xiong, Huabao, Mayer, Lloyd, Berin, Cecilia, Augenlicht, Leonard H., Velcich, Anna, Cerutti, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005805/
https://ncbi.nlm.nih.gov/pubmed/24072822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237910
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