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A systems toxicology approach identifies Lyn as a key signaling phosphoprotein modulated by mercury in a B lymphocyte cell model

Network and protein-protein interaction analyses of proteins undergoing Hg(2+)-induced phosphorylation and dephosphorylation in Hg(2+)-intoxicated mouse WEHI-231 B cells identified Lyn as the most interconnected node. Lyn is a Src family protein tyrosine kinase known to be intimately involved in the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Caruso, Joseph A., Stemmer, Paul M., Dombkowski, Alan, Caruthers, Nicholas J., Gill, Randall, Rosenspire, Allen J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005802/
https://ncbi.nlm.nih.gov/pubmed/24440445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.01.002
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