Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

Salmonella enterica serovar Typhimurium (S. Typhimurium) is a virulent pathogen that induces rapid host death. Here we observed that host survival after infection with S. Typhimurium was enhanced in the absence of type I interferon signaling, with improved survival of mice deficient in the receptor...

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Hlavní autoři: Robinson, Nirmal, McComb, Scott, Mulligan, Rebecca, Dudani, Renu, Krishnan, Lakshmi, Sad, Subash
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005791/
https://ncbi.nlm.nih.gov/pubmed/22922364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2397
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