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Structural biology of the IL-1 superfamily: Key cytokines in the regulation of immune and inflammatory responses

Interleukin-1 superfamily of cytokines (IL-1, IL-18, IL-33) play key roles in inflammation and regulating immunity. The mechanisms of agonism and antagonism in the IL-1 superfamily have been pursued by structural biologists for nearly 20 years. New insights into these mechanisms were recently provid...

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Detalhes bibliográficos
Main Authors: Krumm, Brian, Xiang, Yan, Deng, Junpeng
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-Blackwell 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005705/
https://ncbi.nlm.nih.gov/pubmed/24677376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2441
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